Why Core GRADE is needed: introduction to a new series in The BMJ

This article introduces a series of papers on new guidance for the GRADE (Grading of Recommendations Assessment, Development and Evaluation) approach. Core GRADE was produced in response to the need for a concise, well organised exposition of the key elements of GRADE that users require to make optimal judgments about certainty of evidence and strength of recommendations. This series is primarily aimed at systematic review authors, guideline …