Overview of Hemostasis and Thrombosis

Hemostasis is the balance that maintains the fluid state of blood while preventing bleeding in response to vessel injury. This dynamic process involves the vessel wall, circulating blood cells, and soluble proteins in the blood involved in blood clot formation and degradation. Dysregulation of this balance can lead to thrombosis or bleeding, both of which can have fatal outcomes. Our understanding of the regulation of hemostasis has evolved …