Reducing rates of endophthalmitis from intravitreal injections – strategies and areas of controversy

PURPOSE OF REVIEW: Post-injection endophthalmitis (PIE) is the most concerning complication that accompanies intravitreal injections. This review discusses the recent literature in endophthalmitis prophylaxis including types of antisepsis, the use of topical antibiotics, methods of anesthesia, masking, and office-based versus operating room-based injections. RECENT FINDINGS: Povidone iodine (PI) remains the gold standard for PIE prophylaxis. …