AB1469 PROSPECTIVE REGISTRATION IN RHEUMATOLOGY RANDOMIZED CONTROLLED TRIALS: WHERE WE ARE, WHY, AND HOW WE COULD GET BETTER

Background: Transparent trial conduct requires prospective trial registration, the publication of the protocol of a randomized controlled trial (RCT) before enrolment of the first participant. Its main purpose is to minimize the risk of bias through unjustified or hidden modification of trial design during the course of study, and to ensure that the analyses are performed following a specific hypothesis and would not be driven by the data. …