Journal article
Remdesivir and three other drugs for hospitalised patients with COVID-19: final results of the WHO Solidarity randomised trial and updated meta-analyses
Abstract
BACKGROUND: The Solidarity trial among COVID-19 inpatients has previously reported interim mortality analyses for four repurposed antiviral drugs. Lopinavir, hydroxychloroquine, and interferon (IFN)-β1a were discontinued for futility but randomisation to remdesivir continued. Here, we report the final results of Solidarity and meta-analyses of mortality in all relevant trials to date.
METHODS: Solidarity enrolled consenting adults (aged ≥18 …
Authors
Pan H; Peto R; Henao Restrepo AM; Preziosi M-P; Sathiyamoorthy V; Karim QA; Alejandria M; Hernàndez García C; Kieny M-P; Malekzadeh R
Journal
The Lancet, Vol. 399, No. 10339, pp. 1941–1953
Publisher
Elsevier
Publication Date
5 2022
DOI
10.1016/s0140-6736(22)00519-0
ISSN
0140-6736