Epinephrine for food-induced anaphylaxis: Dose, route, and timing of administration

Prompt administration of intramuscular (IM) epinephrine is the recommended first-line treatment for food-induced anaphylaxis. An epinephrine autoinjector (EAI) is a device that contains a premeasured dose of epinephrine and an autoinjector needle. EAIs are only available in a limited number of doses and are not universally accessible. Potential alternatives to EAIs include epinephrine prefilled syringes (EPSs) and ampoules or vials of epinephrine. More research is needed to compare the usability, sterility, and stability of different delivery methods. Some cases of anaphylaxis require multiple doses of epinephrine to treat.