In 2015, 231,840 American women were diagnosed with invasive breast cancer. This figure represents mothers, wives, or sisters diagnosed with cancer, a diagnosis which has the potential to affect those closest to them, especially their immediate family. This research aimed to examine the lived experience of a family unit that lost their spouse/mother/sister-in-law to invasive breast cancer. A phenomenological case study was utilized to guide this research. One family unit, consisting of a spouse, daughter, son, and sister-in-law to the deceased were recruited from Southern Ontario, Canada. Background questionnaires and one-on-one semi-structured interviews were conducted. The following themes emerged: (1) negatives, describing struggles with balancing care, faith, and living after a death in the family and (2) silver linings, depicting the strength that Nancy, the deceased, maintained during her illness, and the family’s hope and optimism for the future. This paper only addresses the theme “Negatives,” while the last theme is addressed in Part II of this research. Within the theme “Negatives,” there were four sub-themes: (1) What About the Kids? (2) The Balancing Act, (3) Why Would He Do This? and (4) Life After Mom. Each will be discussed in turn. This research study provides valuable information regarding the lived experiences of families coping with a parental/spousal cancer diagnosis. It may assist other individuals in similar situations by providing comfort knowing that they are not the only ones encountering this journey. The participants’ voices may also allow others to develop strength by understanding the effect of cancer on a family.