Journal article
Angiotensin II Activates a Nitric-Oxide-Driven Inhibitory Feedback in the Rat Paraventricular Nucleus
Abstract
The hypothalamic paraventricular nucleus (PVN) has been shown to play major obligatory roles in autonomic and neuroendocrine regulation. Angiotensin II (ANG) acts as a neurotransmitter regulating the excitability of magnocellular neurons in this nucleus. We report here that ANG also activates a nitric-oxide-mediated negative feedback loop in the PVN that acts to regulate the functional output of magnocellular neurons. Thus in addition to its …
Authors
Latchford KJ; Ferguson AV
Journal
Journal of Neurophysiology, Vol. 89, No. 3, pp. 1238–1244
Publisher
American Physiological Society
Publication Date
March 1, 2003
DOI
10.1152/jn.00914.2002
ISSN
0022-3077