Journal article
TMET-24. MULTI-OMIC CHARACTERIZATION OF THE TEMPORAL METABOLIC ADAPTATIONS UNDERPINNING THERAPY RESISTANCE AND TUMOR RECURRENCE IN GLIOBLASTOMA
Abstract
Abstract Therapy resistance and tumor recurrence are barriers to achieving long-term survival in cancer patients, particularly evident in glioblastoma (GBM), known for its dismal 5-year survival rate below 10%. Despite aggressive treatment regimens, including maximal resection, alkylating chemotherapy, and radiation, the majority of GBM patients experience relapse within 7-9 months post-initial intervention. Recurrent GBM poses surgical …
Authors
Martell E; Kuzmychova H; Senthil H; Kaul E; Chawla U; Banerji V; Anderson CM; Venugopal C; Miller D; Werbowetski-Ogilvie TE
Journal
Neuro-Oncology, Vol. 26, No. Supplement_8, pp. viii293–viii293
Publisher
Oxford University Press (OUP)
Publication Date
November 11, 2024
DOI
10.1093/neuonc/noae165.1162
ISSN
1522-8517