3138 – A TWO-STEP IN VIVO CRISPR SCREEN UNVEILS PERVASIVE RNA-BINDING PROTEIN DEPENDENCIES FOR LEUKEMIC STEM CELLS AND IDENTIFIES ELAVL1 AS A THERAPEUTIC TARGET
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1.1 Normal biological development and functioning
2.1 Biological and endogenous factors
32 Biomedical and Clinical Sciences
3201 Cardiovascular Medicine and Haematology
5.1 Pharmaceuticals
Cancer
Childhood Leukemia
Genetics
Hematology
Orphan Drug
Pediatric
Pediatric Cancer
Rare Diseases
Stem Cell Research
Stem Cell Research - Nonembryonic - Human
Stem Cell Research - Nonembryonic - Non-Human
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