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Colchicine for secondary prevention of ischaemic...
Journal article

Colchicine for secondary prevention of ischaemic stroke and atherosclerotic events: a meta-analysis of randomised trials

Abstract

Background: Guidelines recommend low-dose colchicine for secondary prevention in cardiovascular disease, but uncertainty remains concerning its efficacy for stroke, efficacy in key subgroups and about uncommon but serious safety outcomes. Methods: In this trial-level meta-analysis, we searched bibliographic databases and trial registries form inception to May 16, 2024. We included randomised trials of colchicine for secondary prevention of …

Authors

Fiolet ATL; Poorthuis MHF; Opstal TSJ; Amarenco P; Boczar KE; Buysschaert I; Budgeon C; Chan NC; Cornel JH; Jolly SS

Journal

EClinicalMedicine, Vol. 76, ,

Publisher

Elsevier

Publication Date

10 2024

DOI

10.1016/j.eclinm.2024.102835

ISSN

2589-5370