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Human stem cell models unravel mechanisms of...
Journal article

Human stem cell models unravel mechanisms of somite segmentation

Abstract

In vitro models to study human somitogenesis, the formation of the segmented body plan, have so far been limited.1 Two papers in Nature now report the creation of pluripotent stem cell (PSC)-derived 3D culture systems that recapitulate the formation of somite-like structures and help gain insights into this developmental process.2,3.

Authors

Simsek MF; Özbudak EM

Journal

Cell Stem Cell, Vol. 30, No. 3, pp. 246–247

Publisher

Elsevier

Publication Date

3 2023

DOI

10.1016/j.stem.2023.01.011

ISSN

1934-5909