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Candida auris Forms High-Burden Biofilms in Skin...
Journal article

Candida auris Forms High-Burden Biofilms in Skin Niche Conditions and on Porcine Skin

Abstract

Emerging pathogen Candida auris causes nosocomial outbreaks of life-threatening invasive candidiasis. It is unclear how this species colonizes skin and spreads in health care facilities. Here, we analyzed C. auris growth in synthetic sweat medium designed to mimic axillary skin conditions. We show that C. auris demonstrates a high capacity for biofilm formation in this milieu, well beyond that observed for the most commonly isolated Candida

Authors

Horton MV; Johnson CJ; Kernien JF; Patel TD; Lam BC; Cheong JZA; Meudt JJ; Shanmuganayagam D; Kalan LR; Nett JE

Journal

mSphere, Vol. 5, No. 1, pp. 10.1128/msphere.00910–10.1128/msphere.00919

Publisher

American Society for Microbiology

Publication Date

February 26, 2020

DOI

10.1128/msphere.00910-19

ISSN

1556-6811

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