Utilization analysis of drug efficacy of the 329 cases of wenchuan earthquake women and children patients

Objective To study medication usage in women and children from the distress area related to the Wenchuan earthquake. Methods Information about which medications that 329 patients used in West China Second University Hospital, Sichuan University was collected by the HIS system and classified by using the ICD-10system. The cases and times of medication, the total number of drugs, the drug cost per capita, and the drug cost per day were calculated using Excel. The defined daily dose (DDD) and drug utilization index (DUI) were analyzed. According to the principle of DDD & DUI, CDDD & CDUI were designed to analyze the drugs used by children. Results A total of 398 drugs in 25 categories were applied to 329 patients. Every case used infusion solutions, the DDDs of vitamins were the highest, the usage and duration of vitamins and antibacterial agents were the longest among the 25 kinds of the drugs. The cost of Amoxicillin Sulbactam injection was the highest. Many kinds of medications were prescribed to these patients,the rate of DUI>1 vs DUI<1 are 32.3% & 47.2%. The results of CDUI indicated overuse of drugs was serious in children less 1yr old.The CDUI of precortisyl was the highest:40 to 80. Conclusions The system for distribution of medication to patients to children and women during an emergency is flawed. According to our findings we make new suggestions for changes, which have to be proved by further research. © 2009 Editorial Board of Chin J Evid-based Med.