Effects of isoetharine on airways resistance, heart rate, and contractions of the soleus muscle of the anaesthetised cat

The actions of the sympathomimetic bronchodilator, isoetharine, were compared with those of laevoisoprenaline, racemic isoprenaline and salbutamol, on the heart and lungs and on contractions of the soleus muscle of cats under chloralose anaesthesia. Isoetharine and salbutamol injected i.v. were approximately equipotent in all tests, and were about 8 times less potent than laevoisoprenaline both in decreasing the tension and degree of fusion of …