Journal article
Abstract B43: Division of labor between YAP and TAZ in lung cancer
Abstract
Abstract
Paralogs originating from a gene duplication event can diverge and accumulate changes that contribute to a division of labor. Therefore, we wished to explore differential activities of YAP and TAZ. Traditionally, research has tended to consider YAP and TAZ as functionally redundant transcriptional cofactors, with similar biologic impact. However, there is growing evidence that each of them possesses distinct …
Authors
Shreberk-Shaked M; Dassa B; Di Agostino S; Nuriel Y; Wigoda N; Rotkopf R; Blandino G; Aylon Y; Oren M
Journal
Molecular Cancer Research, Vol. 18, No. 8_Supplement, pp. b43–b43
Publisher
American Association for Cancer Research (AACR)
Publication Date
August 1, 2020
DOI
10.1158/1557-3125.hippo19-b43
ISSN
1541-7786