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Benznidazole and Posaconazole in Eliminating...
Journal article

Benznidazole and Posaconazole in Eliminating Parasites in Asymptomatic T. Cruzi Carriers The STOP-CHAGAS Trial

Abstract

BACKGROUND: Benznidazole is recommended for treatment of Chagas infection. Effects of combination therapy with benznidazole and posaconazole have not been tested in Trypanosoma cruzi carriers. OBJECTIVES: The purpose of this study was to determine whether posaconazole alone or combined with benznidazole were superior to benznidazole monotherapy in eliminating T. cruzi parasites measured by real time polymerase chain reaction (RT-PCR) in …

Authors

Morillo CA; Waskin H; Sosa-Estani S; del Carmen Bangher M; Cuneo C; Milesi R; Mallagray M; Apt W; Beloscar J; Gascon J

Journal

Journal of the American College of Cardiology, Vol. 69, No. 8, pp. 939–947

Publisher

Elsevier

Publication Date

2 2017

DOI

10.1016/j.jacc.2016.12.023

ISSN

0735-1097