Journal article
Molecular Mechanisms Underlying Loss of Vascular and Epithelial Integrity in Irritable Bowel Syndrome
Abstract
BACKGROUND & AIMS: The pathophysiology of irritable bowel syndrome (IBS) is multifactorial and includes epithelial barrier dysfunction, a key element at the interface between the gut lumen and the deeper intestinal layers. Beneath the epithelial barrier there is the vascular one representing the last barrier to avoid luminal antigen dissemination The aims of this study were to correlate morpho-functional aspects of epithelial and vascular …
Authors
Barbaro MR; Cremon C; Marasco G; Savarino E; Guglielmetti S; Bonomini F; Palombo M; Fuschi D; Rotondo L; Mantegazza G
Journal
Gastroenterology, Vol. 167, No. 6, pp. 1152–1166
Publisher
Elsevier
Publication Date
November 2024
DOI
10.1053/j.gastro.2024.07.004
ISSN
0016-5085