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Association between serum estradiol and...
Journal article

Association between serum estradiol and cardiovascular health among transgender adults using gender-affirming estrogen therapy

Abstract

Gender-affirming estrogen therapy (GAET) is commonly used for feminization in transgender and nonbinary (TNB) individuals, yet the optimal rate of change (ROC) in estradiol levels for cardiovascular health is unclear. We examined the association between serum estradiol levels and cardiovascular-related mortality, adverse events, and risk factors in TNB adults using GAET. Cochrane Central Register of Controlled Trials, EMBASE, MEDLINE, and Web …

Authors

Rytz CL; Miranda KT; Ronksley PE; Saad N; Raj SR; Somayaji R; Dumanski SM; Ganshorn H; Greene DN; Collister D

Journal

AJP Heart and Circulatory Physiology, Vol. 327, No. 2, pp. h340–h348

Publisher

American Physiological Society

Publication Date

August 1, 2024

DOI

10.1152/ajpheart.00151.2024

ISSN

0363-6135