Enhanced theranostic efficacy of epirubicin-loaded SPION@MSN through co-delivery of an anti-miR-21-expressing plasmid and ZIF-8 hybridization to target colon adenocarcinoma Journal Articles

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abstract

The SPION@MSN-EPI/pDNA-ZIF-8-PEG-Apt nanocarrier showcases exceptional plasmid stability, drug loading, and controlled release. Its outstanding anti-tumor efficacy through targeted chemo–gene therapy is supported by its imaging traceability.

authors

Abrishami, Amir
Bahrami, Ahmad Reza
Saljooghi, Amir Sh
Matin, Maryam M

publication date

March 21, 2024

has subject area

02 Physical Sciences (FoR)
03 Chemical Sciences (FoR)
10 Technology (FoR)
Adenocarcinoma (MeSH)
Animals (MeSH)
Antagomirs (MeSH)
Cell Line, Tumor (MeSH)
Colonic Neoplasms (MeSH)
Drug Delivery Systems (MeSH)
Epirubicin (MeSH)
Magnetic Iron Oxide Nanoparticles (MeSH)
Mice (MeSH)
MicroRNAs (MeSH)
Nanoparticles (MeSH)
Nanoscience & Nanotechnology (Science Metrix)
Polyethylene Glycols (MeSH)
Precision Medicine (MeSH)
Silicon Dioxide (MeSH)

published in

Nanoscale Journal