Journal article
A63 RESTRAINED STRESS IN MICE INDUCES TRANSLOCATION OF GUT COMMENSAL BACTERIAL INTO DISTAL ORGANS
Abstract
AbstractBackground
Bacterial translocation is defined as the migration of bacteria from the intestinal lumen into extraintestinal tissues; this process has been implicated in the pathophysiology of gastrointestinal disorders including irritable bowel syndrome (IBS) and central nervous system disorders. In our recent study, we found that gut bacteria from patients with IBS can disrupt the mucus layer and penetrate into the lamina propria in our …
Authors
Shimbori C; Kraimi N; Lu J; De Palma G; Collins S; Bercik P
Journal
Journal of the Canadian Association of Gastroenterology, Vol. 7, No. Supplement_1, pp. 42–43
Publisher
Oxford University Press (OUP)
Publication Date
February 14, 2024
DOI
10.1093/jcag/gwad061.063
ISSN
2515-2084