Protecting group-free introduction of amino acids to polymers through the aza-Michael reaction

The incorporation of natural amino acids onto a silicone framework is efficiently and simply achieved, without protecting groups or solvents, by using aza-Michael addition to acrylate-modified silicones. Amino acids are natural and versatile building blocks that offer inherent biocompatibility, zwitterionic character, and diverse functional groups, making them attractive for a range of applications. Integrating amino acids into materials can …