Journal article
Phenotypic and transcriptional changes in lens epithelial cells following acute and fractionated ionizing radiation exposure
Abstract
PURPOSE: Exposure to ionizing radiation is one of the known risk factors for the development of lens opacities. It is believed that radiation interactions with lens epithelial cells (LEC) are the underlying cause of cataract development, however, the exact mechanisms have yet to be identified. The aim of this study was to investigate how different radiation dose and fractionation impact normal LEC function.
MATERIALS AND METHODS: A human …
Authors
Vigneux G; Laframboise T; Tharmalingam S; Thome C
Journal
International Journal of Radiation Biology, Vol. 100, No. 4, pp. 573–583
Publisher
Taylor & Francis
Publication Date
April 2, 2024
DOI
10.1080/09553002.2023.2295965
ISSN
0955-3002