Journal article
Kinetic analysis of oncolytic OrfV-induced innate and adaptive immune responses in a murine model of late-stage ovarian cancer
Abstract
Immunotherapies revive host immune responses against tumors by stimulating innate and adaptive immune effector cells with antitumor functions. Thus, detailed studies of immunological cell phenotypes and functions within the tumor microenvironment (TME) following immunotherapy treatments is critical to identifying the determinants of therapeutic success, optimizing treatment regimens, and driving curative outcomes. Oncolytic viruses such as Orf …
Authors
Minott JA; van Vloten JP; Yates JGE; Santry LA; Matuszewska K; Pereira M; Goens MM; Viloria-Petit AM; Wood GA; Karimi K
Journal
Molecular Therapy Oncology, Vol. 31, ,
Publisher
Elsevier
Publication Date
12 2023
DOI
10.1016/j.omto.2023.100748
ISSN
2372-7705