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Analysis of Immune Responses against a Wide Range...
Journal article

Analysis of Immune Responses against a Wide Range of Mycobacterium tuberculosis Antigens in Patients with Active Pulmonary Tuberculosis

Abstract

Characterizing host immune responses to molecular targets of Mycobacterium tuberculosis is essential to develop effective immunodiagnostics and better vaccines. We investigated the immune response against a large series of M. tuberculosis antigens, including 5 classical and 64 nonclassical (39 DosR regulon-encoded, 4 resuscitation-promoting factor [RPF], and 21 reactivation-associated) antigens in active-pulmonary-tuberculosis (TB) patients. …

Authors

Kassa D; Ran L; Geberemeskel W; Tebeje M; Alemu A; Selase A; Tegbaru B; Franken KLMC; Friggen AH; van Meijgaarden KE

Journal

mSphere, Vol. 19, No. 12, pp. 1907–1915

Publisher

American Society for Microbiology

Publication Date

12 2012

DOI

10.1128/cvi.00482-12

ISSN

1556-6811