Journal article
Absence of APOL1 Risk Variants Protects against HIV-Associated Nephropathy in the Ethiopian Population
Abstract
BACKGROUND: Susceptibility to end-stage kidney disease (ESKD) among HIV-infected Americans of African ancestral heritage has been attributed to APOL1 genetic variation. We determined the frequency of the APOL1 G1 and G2 risk variants together with the prevalence of HIV-associated nephropathy (HIVAN) among individuals of Ethiopian ancestry to determine whether the kidney disease genetic risk is PanAfrican or restricted to West Africa, and can …
Authors
Behar DM; Kedem E; Rosset S; Haileselassie Y; Tzur S; Kra-Oz Z; Wasser WG; Shenhar Y; Shahar E; Hassoun G
Journal
American Journal of Nephrology, Vol. 34, No. 5, pp. 452–459
Publisher
Karger Publishers
Publication Date
2011
DOI
10.1159/000332378
ISSN
0250-8095