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Journal article

Real-World Safety and Effectiveness of a Bevacizumab Biosimilar (ABP 215) in Metastatic Colorectal Cancer Patients in Canada

Abstract

BACKGROUND: ABP 215 is a biosimilar to the reference product, bevacizumab, and was one of the first biosimilars approved by Health Canada for the first-line treatment of metastatic colorectal cancer (mCRC). This study aimed to address gaps in real-world evidence (RWE) including patient characteristics, treatment safety (primary objective), and effectiveness (secondary objective) for first-line ABP 215 therapy in Canadian patients with mCRC.

Authors

Cheung WY; Samimi S; Ma K; Knight GJ; Kassam S; Colwell B; Beaudoin A; Vincent MD; Trinkaus M; Filion A

Journal

Clinical Colorectal Cancer, Vol. 23, No. 1, pp. 46–57.e4

Publisher

Elsevier

Publication Date

March 2024

DOI

10.1016/j.clcc.2023.10.007

ISSN

1533-0028