Journal article
Pharmacological Therapies for the Management of Fistulizing Crohn’s Disease: A Systematic Review and Meta-Analysis
Abstract
BACKGROUND: Fistulas are a debilitating complication of Crohn's disease [CD]. We conducted a systematic review to assess the efficacy of medical therapies for fistulizing CD.
METHODS: MEDLINE, Embase, and CENTRAL were searched on May 26, 2022, for randomized controlled trials [RCTs] of pharmacological therapy in adults with fistulizing CD. The primary outcome was induction and maintenance of fistula response. Pooled risk ratios [RRs] and 95% …
Authors
Vuyyuru SK; Solitano V; Narula N; Lee MJ; MacDonald JK; McCurdy JD; Singh S; Ma C; Jairath V
Journal
Journal of Crohn's and Colitis, Vol. 18, No. 4, pp. 589–603
Publisher
Oxford University Press (OUP)
Publication Date
April 23, 2024
DOI
10.1093/ecco-jcc/jjad185
ISSN
1197-4982