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Sex-Specific Effect of CARM1 in Skeletal Muscle...
Journal article

Sex-Specific Effect of CARM1 in Skeletal Muscle Adaptations to Exercise

Abstract

PURPOSE: The purpose of this study was to determine how the intersection of coactivator-associated arginine methyltransferase 1 (CARM1) and biological sex affects skeletal muscle adaptations to chronic physical activity. METHODS: Twelve-week-old female (F) and male (M) wild-type (WT) and CARM1 skeletal muscle-specific knockout (mKO) mice were randomly assigned to sedentary (SED) or voluntary wheel running (VWR) experimental groups. For 8 wk, …

Authors

VANLIESHOUT TL; STOUTH DW; RAZIEE R; SRAKA A-SJ; MASOOD HA; NG SY; MATTINA SR; MIKHAIL AI; MANTA A; LJUBICIC V

Journal

Medicine & Science in Sports & Exercise, Vol. 56, No. 3, pp. 486–498

Publisher

Wolters Kluwer

Publication Date

3 2024

DOI

10.1249/mss.0000000000003333

ISSN

0195-9131