A method for encoding information in DNA sequences is described. The method
is based on the precision-resolution framework, and is aimed to work in
conjunction with a recently suggested terminator-free template independent DNA
synthesis method. The suggested method optimizes the amount of information bits
per synthesis time unit, namely, the writing rate. Additionally, the encoding
scheme studied here takes into account the existence of multiple copies of the
DNA sequence, which are independently distorted. Finally, quantizers for
various run-length distributions are designed.