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Combined proteomic/transcriptomic signature of...
Journal article

Combined proteomic/transcriptomic signature of recurrence post-liver transplantation for hepatocellular carcinoma beyond Milan

Abstract

Background and aimsLiver transplantation (LT) can be offered to patients with Hepatocellular carcinoma (HCC) beyond Milan criteria. However, there are currently limited molecular markers on HCC explant histology to predict recurrence, which arises in up to 20% of LT recipients. The goal of our study was to derive a combined proteomic/transcriptomic signature on HCC explant predictive of recurrence post-transplant using unbiased, high-throughput …

Authors

Bhat M; Clotet-Freixas S; Baciu C; Pasini E; Hammad A; Ivanics T; Reid S; Azhie A; Angeli M; Ghanekar A

Journal

Clinical Proteomics, Vol. 18, No. 1,

Publisher

Springer Nature

Publication Date

12 2021

DOI

10.1186/s12014-021-09333-x

ISSN

1542-6416