Journal article
Transcriptome profiling and proteomic validation reveals targets of the androgen receptor signaling in the BT-474 breast cancer cell line
Abstract
BackgroundAccumulating evidence suggests that the androgen receptor (AR) and its endogenous ligands influence disease progression in breast cancer (BCa). However, AR-mediated changes in BCa differ among the various BCa subtypes according to their hormone receptor profile [i.e., presence/absence of estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor 2, (HER2)]. Thus, we explored the androgen-regulated …
Authors
Vasiliou SK; Filippou PS; Clotet-Freixas S; Soosaipillai A; Batruch I; Viktor Tsianos F; Konvalinka A; Diamandis EP
Journal
Clinical Proteomics, Vol. 19, No. 1,
Publisher
Springer Nature
Publication Date
12 2022
DOI
10.1186/s12014-022-09352-2
ISSN
1542-6416