Journal article
Unravelling the Role of Uncommon Hydrogen Bonds in Cyclodextrin Ferrociphenol Supramolecular Complexes: A Computational Modelling and Experimental Study
Abstract
We sought to determine the cyclodextrins (CDs) best suited to solubilize a patented succinimido-ferrocidiphenol (SuccFerr), a compound from the ferrociphenol family having powerful anticancer activity but low water solubility. Phase solubility experiments and computational modelling were carried out on various CDs. For the latter, several CD-SuccFerr complexes were built starting from combinations of one or two CD(s) where the methylation of CD …
Authors
Pigeon P; Najlaoui F; McGlinchey MJ; García JS; Jaouen G; Gibaud S
Journal
International Journal of Molecular Sciences, Vol. 24, No. 15,
Publisher
MDPI
DOI
10.3390/ijms241512288
ISSN
1661-6596