Large-Scale Functional Hyperconnectivity Patterns Characterizing Trauma-Related Dissociation: A rs-fMRI Study of PTSD and its Dissociative Subtype

Background: In 2012, a dissociative subtype of post-traumatic stress disorder (PTSD) was introduced into the DSM based on emerging clinical and neurobiological evidence of a distinct PTSD phenotype characterized by trauma-related dissociation. Ten years later, considerable research has demonstrated unique small-scale (i.e., node-based) and large-scale (i.e., network-related) functional connectivity patterns, specific to the dissociative …