Journal article
Fixed-Dose Combination Therapy for the Prevention of Cardiovascular Diseases in CKD
Abstract
BACKGROUND: Fixed-dose combination treatments reduce cardiovascular disease in primary prevention. We aim to explore whether those benefits differ in the presence of CKD.
METHODS: We conducted an individual participant data meta-analysis in 18,162 participants on the efficacy and safety of treatment for the primary prevention of cardiovascular disease. Combination therapies consisted of at least two BP-lowering drugs and a statin, with or …
Authors
Sepanlou SG; Mann JFE; Joseph P; Pais P; Gao P; Sharafkhah M; Roshandel G; Yusuf S; Malekzadeh R; Collaboration OBOTPT
Journal
Clinical Journal of the American Society of Nephrology, Vol. 18, No. 11, pp. 1408–1415
Publisher
Wolters Kluwer
Publication Date
11 2023
DOI
10.2215/cjn.0000000000000251
ISSN
1555-9041