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SUN-722 Liver Leptin Receptor Gene Network...
Journal article

SUN-722 Liver Leptin Receptor Gene Network Moderates the Effects of Early Life Adversity on Anxiety and Depression Problems in Children and Adolescents

Abstract

Abstract Leptin is a hormone involved in the regulation of food intake, with receptors largely expressed centrally and peripherally, in structures like the hypothalamus and the liver. Beyond its well-known actions as an energy-balance regulator, leptin is linked to psychiatric disorders. Considering that the association between genetic and early environmental factors contributes to psychopathology, disruptions of leptin …

Authors

de Lima RMS; Barth B; Arcego DM; de Mendonça Filho EJ; Patel S; Wang Z; Pokhvisneva I; Sassi RB; Hall GBC; de Vasconcellos Bittencourt APS

Journal

Journal of the Endocrine Society, Vol. 4, No. Supplement_1, pp. sun–722

Publisher

The Endocrine Society

Publication Date

May 8, 2020

DOI

10.1210/jendso/bvaa046.1034

ISSN

2472-1972