Afferente intestinale Sensibilität während des postoperativen Ileus bei der Maus — ein neues in vitro Modell

IntroductionNonobstructive ileus, signifying the impairment of coordinated propulsive intestinal motility, remains a frequently documented and almost inevitable consequence of open abdominal surgery and sepsis. Animal models suggest that both neuronal and local inflammatory responses are involved. Altered sensory mechanisms are believed to contribute but this has not been investigated directly. Here we describe the results of an in vitro …