Journal article
Suppression of LINC00707 alleviates lipopolysaccharide-induced inflammation and apoptosis in PC-12 cells by regulated miR-30a-5p/Neurod 1
Abstract
Long noncoding RNA (lncRNA) has emerged as a pivotal regulator improving neural regeneration in the progression of spinal cord injury (SCI). However, whether lncRNAs can be targeted for therapeutic intervention of SCI remains unclear. In this study, we found that LINC00707 expression was significantly up-regulated in lipopolysaccharide (LPS)-treated PC-12, a model that mimics nerve cell injury in an inflammatory environment after SCI. …
Authors
Zhu S; Zhou Z; Li Z; Shao J; Jiao G; Huang YE; Lin Y
Journal
Bioscience Biotechnology and Biochemistry, Vol. 83, No. 11, pp. 1–8
Publisher
Taylor & Francis
Publication Date
November 2, 2019
DOI
10.1080/09168451.2019.1637245
ISSN
0916-8451