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The Carotid Body “Tripartite Synapse”: Role of...
Journal article

The Carotid Body “Tripartite Synapse”: Role of Gliotransmission

Abstract

In mammals, cardiorespiratory reflexes originating in the carotid body (CB) help maintain homeostasis by matching oxygen supply to oxygen demand. CB output to the brainstem is shaped by synaptic interactions at a “tripartite synapse” consisting of chemosensory (type I) cells, abutting glial-like (type II) cells, and sensory (petrosal) nerve terminals. Type I cells are stimulated by several blood-borne metabolic stimuli, including the novel …

Authors

Leonard EM; Nurse CA

Journal

Advances in Experimental Medicine and Biology, Vol. 1427, , pp. 185–194

Publisher

Springer Nature

Publication Date

2023

DOI

10.1007/978-3-031-32371-3_20

ISSN

0065-2598