Journal article
Efficacy and Safety of Advanced Oral Small Molecules for Inflammatory Bowel Disease: Systematic Review and Meta-Analysis
Abstract
BACKGROUND AND AIMS: Oral small-molecule drugs [SMDs] are expanding the therapeutic landscape for inflammatory bowel disease [IBD]. This systematic review and meta-analysis summarizes the efficacy and safety of JAK inhibitor [JAKi] and sphingosine-1-phosphate [S1P] receptor modulator treatments for ulcerative colitis [UC] and Crohn's disease [CD].
METHODS: MEDLINE, Embase, and CENTRAL were searched from inception to May 30, 2022. Randomized …
Authors
Solitano V; Vuyyuru SK; MacDonald JK; Zayadi A; Parker CE; Narula N; Peyrin-Biroulet L; Danese S; Feagan BG; Singh S
Journal
Journal of Crohn's and Colitis, Vol. 17, No. 11, pp. 1800–1816
Publisher
Oxford University Press (OUP)
Publication Date
November 24, 2023
DOI
10.1093/ecco-jcc/jjad100
ISSN
1197-4982