Journal article
Assessing Oral Epithelial Dysplasia Risk for Transformation to Cancer: Comparison Between Histologic Grading Systems Versus S100A7 Immunohistochemical Signature-based Grading
Abstract
While a 3-tier oral epithelial dysplasia grading system has been utilized for decades, it is widely recognized as a suboptimal risk indicator for transformation to cancer. A 2-tier grading system has been proposed, although not yet validated. In this study, the 3-tier and 2-tier dysplasia grading systems, and an S100A7 immunohistochemical signature-based grading system were compared to assess prediction of risk of transformation to oral cancer. …
Authors
Darling MR; Hwang JTK; Dickson BJ; Cutz J-C; Salama S; McCord C; Pritzker KPH; Mock D; Thompson LDR
Journal
Applied Immunohistochemistry & Molecular Morphology, Vol. 31, No. 6, pp. 399–405
Publisher
Wolters Kluwer
Publication Date
July 2023
DOI
10.1097/pai.0000000000001132
ISSN
1541-2016