Reducing Long‐Term Mortality Post Transcatheter Aortic Valve Replacement Requires Systemic Differentiation of Patient‐Specific Coronary Hemodynamics

Background Despite the proven benefits of transcatheter aortic valve replacement (TAVR) and its recent expansion toward the whole risk spectrum, coronary artery disease is present in more than half of the candidates for TAVR. Many previous studies do not focus on the longer-term impact of TAVR on coronary arteries, and hemodynamic changes to the circulatory system in response to the anatomical changes caused by TAVR are not fully understood. …