Journal article
High-Dose Oral Vancomycin for Treatment of Clostridioides difficile Is Associated With High Risk of Subsequent Cultures With Gram-Negative Organisms
Abstract
Background Vancomycin is associated with disruption of the indigenous microbiota, potentially predisposing patients to overgrowth of endogenous pathogens. Our objective was to determine whether high-dose oral vancomycin is associated with cultures growing gram-negative organisms in adult patients with Clostridioides difficile infection (CDI). Methods This is a retrospective cohort study of 632 adult patients with CDI from January 2015 to …
Authors
Bader MS; Someili A; Alosali A; Hadzic A; Irfan N; Leto D; Mertz D; Brooks AA
Journal
Infectious Diseases in Clinical Practice, Vol. 29, No. 6, pp. e361–e365
Publisher
Wolters Kluwer
Publication Date
November 2021
DOI
10.1097/ipc.0000000000001045
ISSN
1056-9103