Cannabis use is associated with sexually dimorphic changes in executive control of visuospatial decision-making

Abstract When the outcome of a choice is less favourable than expected, humans and animals typically shift to an alternate choice option. Several lines of evidence indicate that this “lose-shift” responding is an innate sensorimotor response strategy that is normally suppressed by executive function. Therefore, the lose-shift response provides a covert gauge of cognitive control over choice mechanisms. We report here that the spatial position, …