Composition of the protein layers adsorbed from blood or plasma to solid surfaces: A perspective

The protein layers deposited from blood onto contacting surfaces are believed to be a strong determinant of ultimate thrombogenesis. Recent research on the composition of these layers is reviewed. The layers are complex and contain a multiplicity of components, most of which are not yet identified. The abundant plasma proteins albumin, IgG and fibrinogen are found on most surfaces but in relatively small amounts. Other proteins found are …