Journal article
The hydrogen sulfide donor IK‐1001 stimulates neovascularization and improves wound healing
Abstract
Here we studied the effects of the novel biological mediator hydrogen sulfide (H2S) on angiogenesis and wound healing. We have utilized IK‐1001, an aqueous formulation of H2S. Treatment of chicken chorioallantoic membranes with H2S (0.24–240 pmol/egg) increased vascular length. In vitro, incubation of human umbilical vein endothelial cells with H2S (6 uM to 600 uM concentration) promoted cell growth. In addition, treatment of the cells with H2S …
Authors
Pyiochou A; Papapetropoulos A; Olah G; Wintner E; Jeschke M; Branski L; Herndon D; Traber D; Szabo C
Journal
The FASEB Journal, Vol. 22, No. S1, pp. 912.42–912.42
Publisher
Wiley
Publication Date
March 2008
DOI
10.1096/fasebj.22.1_supplement.912.42
ISSN
0892-6638