Journal article
Polypharmacy and Optimization of Guideline-Directed Medical Therapy in Heart Failure The GUIDE-IT Trial
Abstract
BACKGROUND: Polypharmacy is common among patients with heart failure with reduced ejection fraction (HFrEF). However, its impact on the use of optimal guideline-directed medical therapy (GDMT) is not well established.
OBJECTIVES: This study sought to evaluate the association between polypharmacy and odds of receiving optimal GDMT over time among patients with HFrEF.
Authors
Khan MS; Singh S; Segar MW; Usman MS; Keshvani N; Ambrosy AP; Fiuzat M; Van Spall HGC; Fonarow GC; Zannad F
Journal
JACC Heart Failure, Vol. 11, No. 11, pp. 1507–1517
Publisher
Elsevier
Publication Date
11 2023
DOI
10.1016/j.jchf.2023.03.007
ISSN
2213-1779