Journal article
Effects of adjuvant chemotherapy on the protein C anticoagulant pathway in patients with early stage breast cancer
Abstract
8563
Background: Although chemotherapy treatment is associated with an increased risk of thrombosis, the pathogenic mechanisms are poorly understood. We have previously shown that treatment of endothelial cells with adriamycin and epirubicin impairs the protein C anticoagulant pathway by downregulating EPCR (endothelial protein C receptor), an endothelial receptor required for the conversion of protein C to the anticoagulant …
Authors
Mukherjee SD; Levine M; Beaudin S; Shin L; Caruso S; Liaw P
Journal
Journal of Clinical Oncology, Vol. 24, No. 18_suppl, pp. 8563–8563
Publisher
American Society of Clinical Oncology (ASCO)
Publication Date
June 20, 2006
DOI
10.1200/jco.2006.24.18_suppl.8563
ISSN
0732-183X