Journal article
Renal Recovery for Patients with ANCA-Associated Vasculitis and Low eGFR in the ADVOCATE Trial of Avacopan
Abstract
Introduction: In the 330-patient ADVOCATE trial of avacopan for the treatment of antineutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis, in which 81% of patients had renal involvement, estimated glomerular filtration rate (eGFR) increased on average 7.3 ml/min per 1.73 m2 in the avacopan group and 4.1 ml/min per 1.73 m2 in the prednisone group (P = 0.029) at week 52. This new analysis examines the results in the patient subgroup …
Authors
Cortazar FB; Niles JL; Jayne DRW; Merkel PA; Bruchfeld A; Yue H; Schall TJ; Bekker P; Group S; Peh CA
Journal
Kidney International Reports, Vol. 8, No. 4, pp. 860–870
Publisher
Elsevier
Publication Date
4 2023
DOI
10.1016/j.ekir.2023.01.039
ISSN
2468-0249