Journal article
Endoscopic and Histological Placebo Rates in Crohn’s Disease Clinical Trials: A Systematic Review and Meta-analysis
Abstract
BACKGROUND: Precise estimates of placebo response rates help efficient clinical trial design. In this systematic review and meta-analysis, we assessed contemporary placebo endoscopic and histological response rates in Crohn's disease (CD) clinical trials.
METHODS: MEDLINE, EMBASE, and Cochrane CENTRAL were searched from inception to April 2022 to identify placebo-controlled studies of pharmacological interventions for CD. Endoscopic response, …
Authors
Vuyyuru SK; Nguyen TM; Hogan M; Raine T; Noor NM; Narula N; Verstockt B; Feagan BG; Singh S; Ma C
Journal
Inflammatory Bowel Diseases, Vol. 30, No. 4, pp. 651–659
Publisher
Oxford University Press (OUP)
Publication Date
April 3, 2024
DOI
10.1093/ibd/izad052
ISSN
1078-0998